Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 3/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158365 | 0.77 | LCK (0.39) | PNMTKDM4EMAPTALDH1A1 | |
| SCHEMBL15503053 | 0.76 | PNMT (0.49) | PNMTASIC3 | |
| SCHEMBL4258102 | 0.76 | ALDH1A1 (0.52) | TTRSRD5A1SRD5A2KDM4EMAPT | |
| SCHEMBL31013896 | 0.76 | PNMT (0.49) | PNMTASIC3 | |
| SCHEMBL22938497 | 0.73 | TTR (0.46) | TTRSRD5A1SRD5A2KDM4EMAPT | |
| SCHEMBL25259397 | 0.73 | PNMT (0.53) | PNMTASIC3 | |
| SCHEMBL15503117 | 0.73 | PNMT (0.44) | PNMTASIC3 | |
| SCHEMBL30428318 | 0.71 | ALDH1A1 (0.59) | PNMTASIC3KDM4EMAPTALDH1A1 | |
| SCHEMBL29589725 | 0.71 | ALDH1A1 (0.59) | PNMTKDM4EMAPTALDH1A1 | |
| SCHEMBL1026101 | 0.71 | ALDH1A1 (0.59) | PNMTASIC3KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002165-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2023-01-26 | — | — | WO | disclosed |