Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 6/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24913898 | 0.77 | TTR (0.43) | PNMTKDM4EMAPTALDH1A1 | |
| SCHEMBL3243586 | 0.72 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL1026913 | 0.68 | ALDH1A1 (0.59) | PNMTADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL30428318 | 0.68 | ALDH1A1 (0.59) | PNMTKDM4EMAPTALDH1A1 | |
| SCHEMBL29589725 | 0.68 | ALDH1A1 (0.59) | PNMTADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL1026101 | 0.68 | ALDH1A1 (0.59) | PNMTKDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL15671006 | 0.67 | ALDH1A1 (0.58) | PNMTADRA2AADRA2BADRA2CKDM4E | |
| Hydrochloric Acid SCHEMBL22654009 | 0.67 | ALDH1A1 (0.58) | PNMTKDM4EMAPTALDH1A1 | |
| SCHEMBL29657239 | 0.66 | LCK (0.56) | LCKFYNKDM4EMAPTALDH1A1 | |
| SCHEMBL3841219 | 0.66 | LCK (0.56) | LCKFYNKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777320-B2 | Molecular adaptors for dye conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-9777320-B2 | Molecular adaptors for dye conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-20120058473-A1 | Molecular Adaptors for Dye Conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058473-A1 | Molecular Adaptors for Dye Conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058473-A1 | Molecular Adaptors for Dye Conjugates | ALKBH1, ALKBH5, ALKBH3 | LCK 700/4885FYN 1412/4885PNMT 1241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.