SCHEMBL24914489

SCHEMBL24914489

C#CCN(C)c1cccc(C(=O)Nc2c(I)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)c1F

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSS P25774 2/20 0.37
PTGES O14684 16/20 0.35
RXFP1 Q9HBX9 1/20 0.33
F2R P25116 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23059691 0.91 CTSS (0.35) CTSSPTGESRXFP1F2R
SCHEMBL23059720 0.86 CTSS (0.34) CTSSPTGESRXFP1
SCHEMBL24914808 0.86 CTSS (0.37) CTSSPTGESRXFP1F2R
SCHEMBL24914496 0.86 POLQ (0.38) CTSSPTGESRXFP1
SCHEMBL24914487 0.85 POLQ (0.34) CTSSPTGESRXFP1
SCHEMBL23059604 0.85 CTSS (0.35) CTSSPTGESRXFP1
SCHEMBL23059707 0.84 CTSS (0.35) CTSSPTGESRXFP1
SCHEMBL24914488 0.83 RXFP1 (0.39) CTSSPTGESRXFP1
SCHEMBL24914654 0.82 RXFP1 (0.38) CTSSPTGESRXFP1
SCHEMBL1766647 0.81 CTSS (0.36) CTSSPTGESRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023284645-A1 AMIDE COMPOUND AND USE THEREOF 沈阳化工大学 2023-01-19 WO disclosed