Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24914487 | 0.92 | POLQ (0.34) | RXFP1POLQPTGESCTSSHDAC8 | |
| SCHEMBL24914496 | 0.92 | POLQ (0.38) | RXFP1POLQPTGESCTSSHDAC8 | |
| SCHEMBL24914869 | 0.89 | BRAF (0.32) | POLQPTGESHDAC8 | |
| SCHEMBL24914954 | 0.89 | RXFP1 (0.37) | RXFP1MLYCDTRPM8VNN1PTGES | |
| SCHEMBL21701238 | 0.88 | RXFP1 (0.37) | RXFP1MLYCDVNN1HDAC8 | |
| SCHEMBL31348985 | 0.88 | RXFP1 (0.41) | RXFP1MLYCDTRPM8VNN1TRPV1 | |
| SCHEMBL1766651 | 0.87 | RXFP1 (0.40) | RXFP1MLYCDTRPM8VNN1TRPV1 | |
| SCHEMBL24914865 | 0.87 | P2RX7 (0.33) | POLQPTGESCTSS | |
| SCHEMBL23641883 | 0.85 | RXFP1 (0.38) | RXFP1MLYCDPOLQVNN1TRPV1 | |
| SCHEMBL1766918 | 0.83 | RXFP1 (0.39) | RXFP1MLYCDTRPM8VNN1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284645-A1 | AMIDE COMPOUND AND USE THEREOF | 沈阳化工大学 | 2023-01-19 | — | — | WO | disclosed |