Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029433 | 0.92 | HDAC8 (0.34) | HSD11B1HDAC8SLC6A2SLC6A4GPBAR1 | |
| SCHEMBL21693605 | 0.91 | RXFP1 (0.35) | RXFP1HSD11B1SMOMLYCDHDAC8 | |
| SCHEMBL22029464 | 0.90 | HDAC8 (0.35) | RXFP1HSD11B1HDAC8SLC6A2SLC6A4 | |
| SCHEMBL23053028 | 0.90 | FAAH (0.33) | HDAC8GPBAR1 | |
| SCHEMBL23288057 | 0.89 | RXFP1 (0.42) | RXFP1HSD11B1SMOMLYCDHDAC8 | |
| SCHEMBL29857077 | 0.89 | RXFP1 (0.42) | RXFP1HSD11B1SMOMLYCDHDAC8 | |
| SCHEMBL24914654 | 0.88 | RXFP1 (0.38) | RXFP1MLYCDHDAC8VNN1 | |
| SCHEMBL24914954 | 0.88 | RXFP1 (0.37) | RXFP1MLYCDVNN1 | |
| SCHEMBL24626045 | 0.87 | GPBAR1 (0.34) | MLYCDHDAC8SLC6A2SLC6A4GPBAR1 | |
| SCHEMBL23053046 | 0.86 | P2RX7 (0.37) | MLYCDHDAC8GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030092-A1 | PHARMACEUTICAL COMPOSITION CONTAINING M-DIAMIDE COMPOUND AND APPLICATION THEREOF | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |
| WO-2020030093-A1 | PHARMACEUTICAL COMPOSITION CONTAINING M-DIAMIDE COMPOUND AND APPLICATION THEREOF | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |