Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.33 |
| ▸ | PTGES | O14684 | 4/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23059628 | 0.93 | GPBAR1 (0.34) | P2RX7PTGESPOLQAURKAAURKB | |
| SCHEMBL24914869 | 0.91 | BRAF (0.32) | PTGESPOLQ | |
| SCHEMBL24914487 | 0.90 | POLQ (0.34) | PTGESPOLQCTSS | |
| SCHEMBL24914496 | 0.89 | POLQ (0.38) | PTGESPOLQCTSS | |
| SCHEMBL24914632 | 0.88 | PTGES (0.30) | PTGESAURKAAURKBLCKKDR | |
| SCHEMBL23053046 | 0.88 | P2RX7 (0.37) | P2RX7ACKR3 | |
| SCHEMBL23059713 | 0.87 | GPBAR1 (0.32) | P2RX7 | |
| SCHEMBL24914654 | 0.87 | RXFP1 (0.38) | PTGESPOLQCTSS | |
| SCHEMBL20846770 | 0.86 | GPBAR1 (0.34) | PTGESAURKAAURKBLCKKDR | |
| SCHEMBL24914563 | 0.86 | POLQ (0.31) | PTGESPOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284645-A1 | AMIDE COMPOUND AND USE THEREOF | 沈阳化工大学 | 2023-01-19 | — | — | WO | disclosed |