SCHEMBL24914664

SCHEMBL24914664

c1ccc(-c2nc(-c3cccc(-c4cccc5oc6ccccc6c45)c3)nc(-n3c4ccccc4c4c3ccc3c5ccccc5n(-c5ccccc5)c34)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24914572 0.96 KDM4E (0.34) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL16811463 0.94 KDM4E (0.33) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25965020 0.94 KDM4E (0.31) KDM4EATML3MBTL1
SCHEMBL24914743 0.92 KDM4E (0.34) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL22049944 0.92 ALOX5 (0.38)
SCHEMBL25965333 0.92 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL25965363 0.92 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL24914813 0.91 KDM4E (0.35) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25010837 0.91 PDE10A (0.32)
SCHEMBL25965341 0.91 KDM4E (0.32) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230019297-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230019297-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, SOD1 KDM4E 3351/4885ATM 2183/4885L3MBTL1 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.