Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278987 | 0.87 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL5308928 | 0.83 | TSHR (0.35) | TSHRTHRBALDH1A1 | |
| SCHEMBL29076717 | 0.83 | TSHR (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL1014718 | 0.80 | ALDH1A1 (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL9860071 | 0.78 | TSHR (0.36) | TSHRTHRBALDH1A1 | |
| Hydrogen Sulfide SCHEMBL21253275 | 0.78 | ALDH1A1 (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL2496761 | 0.77 | TSHR (0.37) | TSHR | |
| Hydrogen Sulfide SCHEMBL23421906 | 0.77 | THRB (0.37) | TSHRTHRBALDH1A1 | |
| SCHEMBL29022836 | 0.77 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL8462711 | 0.77 | TSHR (0.35) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279527-B2 | Method of converting anionic living end to protected free radical living end and applications thereof | BRIDGESTONE CORPORATION (JP) | 2007-10-09 | — | — | US | claimed |
| US-20060241265-A1 | Method of converting anionic living end to protected free radical living end and applications thereof | BRIDGESTONE CORPORATION (JP) | 2006-10-26 | — | — | US | claimed |
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | claimed |
| US-8030410-B2 | Reacting anionic living end polymer that is end capped with steric hindering carbonyl-containing compound to produce polymer with homolytically cleaveable group; engineering plastics | BRIDGESTONE CORPORATION (JP) | 2011-10-04 | — | — | US | disclosed |
| US-7737218-B2 | Method for generating free radical capable polymers using tin or silicon halide compounds | BRIDGESTONE CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| US-7560509-B2 | Method of directing grafting by controlling the location of high vinyl segments in a polymer | BRIDGESTONE CORPORATION (JP) | 2009-07-14 | — | — | US | disclosed |
| US-20080161495-A1 | Method for Generating Free Radical Capable Polymers Using Tin or Silicon Halide Compounds | BRIDGESTONE CORPORATION (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20080161484-A1 | Method of Directing Grafting by Controlling the Location of High Vinyl Segments in a Polymer | BRIDGESTONE CORPORATION (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20080161501-A1 | Method for generating free radical capable polymers using carbonyl-containing compounds | BRIDGESTONE CORPORATION (JP) | 2008-07-03 | — | — | US | disclosed |
| US-7279527-B2 | Method of converting anionic living end to protected free radical living end and applications thereof | BRIDGESTONE CORPORATION (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060241265-A1 | Method of converting anionic living end to protected free radical living end and applications thereof | BRIDGESTONE CORPORATION (JP) | 2006-10-26 | — | — | US | disclosed |
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | disclosed |