Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1891367 | 0.77 | GRIA2 (0.50) | L3MBTL1ALDH1A1LMNAKDM6BKDM4A | |
| SCHEMBL1891365 | 0.77 | GRIA2 (0.50) | L3MBTL1ALDH1A1LMNAKDM6BKDM4A | |
| SCHEMBL5591576 | 0.69 | — | — | |
| SCHEMBL24915510 | 0.68 | ALOX15 (0.43) | LTA4HGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL24251553 | 0.65 | NAALAD2 (0.60) | L3MBTL1ALDH1A1LMNAKDM6BKDM4A | |
| SCHEMBL31696740 | 0.65 | NAALAD2 (0.60) | L3MBTL1ALDH1A1LMNAKDM6BKDM4A | |
| SCHEMBL5325386 | 0.64 | PLA2G2C (0.57) | L3MBTL1ALDH1A1LMNAKDM6BKDM4A | |
| SCHEMBL6208476 | 0.62 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1LMNAKDM6BKDM4A | |
| SCHEMBL5841196 | 0.62 | EPHX2 (0.56) | L3MBTL1ALDH1A1LMNAKDM6BKDM4A | |
| SCHEMBL13780257 | 0.62 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1LMNAKDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |