Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14301143 | 0.85 | DDAH1 (0.41) | KMT2ACYP1A2 | |
| SCHEMBL5368134 | 0.85 | CYP2D6 (0.43) | ALOX15BLMPMP22KMT2ACHRM2 | |
| SCHEMBL17305092 | 0.83 | CES2 (0.48) | KMT2ACYP1A2 | |
| SCHEMBL8260805 | 0.79 | DDAH1 (0.37) | ALOX15BLMPMP22KMT2ADPP9 | |
| SCHEMBL11048596 | 0.76 | SLC7A5 (0.50) | ALOX15BLMPMP22KMT2ACHRM2 | |
| SCHEMBL14771690 | 0.73 | GRIK1 (0.38) | ALOX15BLMPMP22KMT2ADPP9 | |
| SCHEMBL21345146 | 0.73 | GRIK1 (0.38) | ALOX15BLMPMP22KMT2ADPP9 | |
| SCHEMBL10068031 | 0.73 | GRIK1 (0.38) | ALOX15BLMPMP22KMT2ADPP9 | |
| SCHEMBL984694 | 0.72 | — | — | |
| SCHEMBL30185314 | 0.71 | ALOX15 (0.38) | ALOX15BLMPMP22KMT2ADPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |