Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 8/20 | 0.54 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24899346 | 0.91 | MMP3 (0.56) | MMP3MMP9MMP8MMP1PTPN1 | |
| SCHEMBL27277512 | 0.87 | MMP3 (0.53) | MMP3MMP9MMP8MMP1PTPN1 | |
| SCHEMBL24899384 | 0.86 | MMP3 (0.52) | MMP3MMP9MMP8MMP1PTPN1 | |
| SCHEMBL26875855 | 0.82 | PTPN1 (0.53) | GPR34PTPN1KLKB1PPARG | |
| SCHEMBL26173250 | 0.82 | PTPN1 (0.58) | GPR34MMP3PTPN1KLKB1PPARG | |
| SCHEMBL26892213 | 0.81 | MME (0.50) | GPR34MMP3PTPN1KLKB1PPARG | |
| SCHEMBL26172463 | 0.81 | MME (0.50) | GPR34MMP3PTPN1KLKB1PPARG | |
| SCHEMBL26888062 | 0.80 | PTPN1 (0.55) | GPR34MMP3MMP1PTPN1KLKB1 | |
| SCHEMBL26889155 | 0.79 | PTPN1 (0.57) | GPR34PTPN1KLKB1PPARG | |
| SCHEMBL26173212 | 0.79 | PTPN1 (0.57) | GPR34PTPN1KLKB1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |