Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 6/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CENPE | Q02224 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24899346 | 0.95 | MMP3 (0.56) | MMP3MMP9MMP8KLKB1MMP2 | |
| SCHEMBL27277512 | 0.91 | MMP3 (0.53) | MMP3MMP9MMP8MMP2MMP1 | |
| SCHEMBL26172463 | 0.87 | MME (0.50) | MMP3KLKB1PTPN1MMEACE | |
| SCHEMBL26892213 | 0.87 | MME (0.50) | MMP3KLKB1PTPN1MMEACE | |
| SCHEMBL24915280 | 0.86 | GPR34 (0.54) | MMP3MMP9MMP8KLKB1MMP2 | |
| SCHEMBL26173250 | 0.86 | PTPN1 (0.58) | MMP3KLKB1PTPN1MMEACE | |
| SCHEMBL26888062 | 0.83 | PTPN1 (0.55) | MMP3KLKB1MMP1PTPN1MME | |
| SCHEMBL26173212 | 0.82 | PTPN1 (0.57) | KLKB1PTPN1MMEACECPA1 | |
| SCHEMBL26889155 | 0.82 | PTPN1 (0.57) | KLKB1PTPN1MMEACECPA1 | |
| SCHEMBL24915270 | 0.81 | PTPN1 (0.48) | MMP3MMP9MMP2MMP1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |