Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 3/20 | 0.32 |
| ▸ | METAP1 | P53582 | 3/20 | 0.32 |
| ▸ | FCER2 | P06734 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26169813 | 0.90 | FCER2 (0.36) | ACEMETAP2METAP1FCER2 | |
| SCHEMBL24915444 | 0.84 | ACE (0.35) | ACEFCER2 | |
| SCHEMBL24916224 | 0.80 | NOD1 (0.34) | ACEFCER2 | |
| SCHEMBL24916247 | 0.80 | CES2 (0.36) | CES2 | |
| SCHEMBL24915216 | 0.77 | MME (0.34) | METAP1CES2 | |
| SCHEMBL24915215 | 0.76 | DPP4 (0.39) | METAP2METAP1FCER2 | |
| SCHEMBL20910230 | 0.75 | FCER2 (0.35) | ACEFCER2 | |
| SCHEMBL26857875 | 0.74 | MME (0.33) | — | |
| SCHEMBL26774841 | 0.74 | MME (0.36) | ACECES2 | |
| SCHEMBL24713146 | 0.72 | ACE (0.40) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102507-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |