Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 8/20 | 0.36 |
| ▸ | METAP1 | P53582 | 5/20 | 0.36 |
| ▸ | ECE1 | P42892 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26169813 | 0.86 | FCER2 (0.36) | DPP4DPP8DPP9FCER2METAP2 | |
| SCHEMBL21201558 | 0.83 | METAP2 (0.39) | DPP4DPP8DPP9METAP2METAP1 | |
| SCHEMBL31447508 | 0.79 | DPP4 (0.42) | DPP4DPP8DPP9ECE1ERAP2 | |
| SCHEMBL30799694 | 0.79 | DPP4 (0.42) | DPP4DPP8DPP9ECE1ERAP2 | |
| SCHEMBL30788713 | 0.77 | DPP4 (0.40) | DPP4DPP8DPP9ERAP2ERAP1 | |
| SCHEMBL19502439 | 0.77 | DPP4 (0.46) | DPP4DPP8DPP9METAP2METAP1 | |
| SCHEMBL30799779 | 0.76 | DPP8 (0.65) | DPP4DPP8DPP9ERAP2ERAP1 | |
| SCHEMBL21955443 | 0.76 | ARG1 (0.36) | NOS2NOS1NOS3 | |
| SCHEMBL24915512 | 0.76 | ACE (0.34) | FCER2METAP2METAP1 | |
| SCHEMBL7313525 | 0.76 | SLC7A5 (0.48) | DPP4DPP8DPP9ERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |