Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | QDPR | P09417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915971 | 1.00 | KCNH2 (0.37) | KCNH2MAP3K14ADRA2APIK3CDPIK3CB | |
| SCHEMBL24915657 | 0.81 | ADRA2A (0.48) | MAP3K14ADRA2APIK3CBPIK3CGKDM4C | |
| SCHEMBL24915969 | 0.81 | ADRA2A (0.48) | MAP3K14ADRA2APIK3CBPIK3CGKDM4C | |
| SCHEMBL12169251 | 0.79 | GRM7 (0.38) | MAP3K14ADRA2A | |
| SCHEMBL16691509 | 0.79 | PTGS1 (0.36) | MAP3K14ADRA2A | |
| SCHEMBL12609031 | 0.79 | GRM7 (0.38) | MAP3K14ADRA2A | |
| SCHEMBL23841478 | 0.79 | MAP3K14 (0.51) | KCNH2MAP3K14ADRA2APIK3CA | |
| SCHEMBL12609027 | 0.79 | GRM7 (0.38) | MAP3K14ADRA2A | |
| SCHEMBL24915967 | 0.77 | ENPP2 (0.46) | — | |
| SCHEMBL24915659 | 0.77 | ENPP2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | KCNH2 4375/4885MAP3K14 868/4885ADRA2A 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.