Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 18/20 | 0.52 |
| ▸ | AURKA | O14965 | 16/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915853 | 0.88 | LMNA (0.50) | RPS6KB1AURKAKDM4ELMNA | |
| SCHEMBL24915857 | 0.85 | LMNA (0.39) | RPS6KB1AURKAKDM4ELMNA | |
| SCHEMBL24915856 | 0.85 | JAK2 (0.42) | RPS6KB1AURKAKDM4ELMNA | |
| SCHEMBL24915854 | 0.85 | MTNR1A (0.43) | RPS6KB1AURKAKDM4ELMNA | |
| SCHEMBL24916220 | 0.84 | DPP4 (0.45) | KDM4ELMNA | |
| SCHEMBL24915862 | 0.81 | HPGD (0.46) | KDM4E | |
| SCHEMBL24915850 | 0.80 | KDM4E (0.47) | AURKAKDM4ELMNA | |
| SCHEMBL24915923 | 0.79 | CD38 (0.45) | RPS6KB1AURKAKDM4E | |
| SCHEMBL24916219 | 0.77 | PDE10A (0.41) | KDM4E | |
| SCHEMBL24915645 | 0.77 | NSD2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | RPS6KB1 683/4885AURKA 918/4885KDM4E 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.