Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 7/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915954 | 0.87 | PRKDC (0.46) | HTR1ALRRK2HTR6NCF1HTR1B | |
| SCHEMBL24915957 | 0.85 | LRRK2 (0.45) | HTR1ALRRK2DRD3NCF1 | |
| SCHEMBL24915959 | 0.84 | LRRK2 (0.45) | ELANEHTR1ALRRK2 | |
| SCHEMBL24915981 | 0.83 | HTR1A (0.38) | ELANEHTR1AHTR6DRD2DRD3 | |
| SCHEMBL24915960 | 0.81 | HTR1A (0.41) | HRH4HTR1ALRRK2HTR6DRD2 | |
| SCHEMBL24916054 | 0.81 | HTR1B (0.41) | ELANEHRH4HTR1AHTR6HTR1B | |
| SCHEMBL24916357 | 0.80 | MAPT (0.47) | HTR6DRD2DRD3 | |
| SCHEMBL24916006 | 0.79 | TLR9 (0.42) | ELANEHTR1AHTR1BHTR1D | |
| SCHEMBL24915645 | 0.74 | NSD2 (0.44) | — | |
| SCHEMBL24916219 | 0.74 | PDE10A (0.41) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | ELANE 4095/4885HRH4 2984/4885HTR1A 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.