Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916038 | 0.95 | KDM4E (0.40) | KDM4EL3MBTL1HSP90AA1HSP90AB1NSD2 | |
| SCHEMBL24916030 | 0.91 | TLR9 (0.37) | KDM4EL3MBTL1CYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL24916365 | 0.85 | NSD2 (0.39) | KDM4EL3MBTL1HSP90AA1HSP90AB1NSD2 | |
| SCHEMBL29923797 | 0.83 | KDM4E (0.38) | KDM4EL3MBTL1HSP90AA1HSP90AB1NSD2 | |
| SCHEMBL24916107 | 0.83 | KDM4E (0.38) | KDM4EL3MBTL1HSP90AA1HSP90AB1NSD2 | |
| SCHEMBL24916430 | 0.81 | NSD2 (0.39) | KDM4EHSP90AA1HSP90AB1NSD2CASP6 | |
| SCHEMBL24916429 | 0.80 | NSD2 (0.39) | KDM4EHSP90AA1HSP90AB1NSD2CASP6 | |
| SCHEMBL24916363 | 0.79 | ALDH1A1 (0.39) | KDM4EL3MBTL1CYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL24916497 | 0.79 | KDM4E (0.41) | KDM4EL3MBTL1NSD2CASP6ALDH1A1 | |
| SCHEMBL24916219 | 0.74 | PDE10A (0.41) | KDM4EL3MBTL1HSP90AA1HSP90AB1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | KDM4E 105/4885L3MBTL1 1214/4885HSP90AA1 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.