Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 9/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.44 |
| ▸ | PBK | Q96KB5 | 5/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916011 | 0.93 | PBK (0.38) | TLR9TLR8TLR7PBK | |
| SCHEMBL24915525 | 0.87 | CNR2 (0.46) | — | |
| SCHEMBL24916196 | 0.82 | PFKFB3 (0.38) | HTR4 | |
| SCHEMBL24915977 | 0.81 | CNR2 (0.42) | TLR9TLR8TLR7PBK | |
| SCHEMBL24915998 | 0.80 | SMYD3 (0.47) | SMYD3 | |
| SCHEMBL24916193 | 0.79 | CSF1R (0.38) | TLR9TLR8TLR7 | |
| SCHEMBL24915997 | 0.79 | GPR52 (0.39) | — | |
| SCHEMBL24915849 | 0.78 | PLK1 (0.37) | — | |
| SCHEMBL24916002 | 0.78 | SMYD3 (0.43) | SMYD3 | |
| SCHEMBL24916013 | 0.78 | MAP4K4 (0.40) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | TLR9 4379/4885TLR8 4298/4885TLR7 4346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.