Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915532 | 0.86 | LMNA (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL24915997 | 0.86 | GPR52 (0.39) | ALDH1A1BRD4 | |
| SCHEMBL24916411 | 0.86 | ACE2 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL24915998 | 0.85 | SMYD3 (0.47) | RAB9AALDH1A1BRD4 | |
| SCHEMBL24916013 | 0.85 | MAP4K4 (0.40) | L3MBTL1HSP90AB1 | |
| SCHEMBL24916033 | 0.85 | RAB9A (0.43) | NPC1RAB9AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL24916409 | 0.84 | GABRA1 (0.43) | NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL24916027 | 0.83 | CSNK2A2 (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL24916002 | 0.83 | SMYD3 (0.43) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL24915854 | 0.80 | MTNR1A (0.43) | PLK1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | PLK1 264/4885SLC40A1 4365/4885NPC1 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.