SCHEMBL24916731

SCHEMBL24916731

c1ccc(CCC2c3ccccc3CCN2c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.52
ESR2 Q92731 2/20 0.52
SIGMAR1 Q99720 5/20 0.46
GRIN1 Q05586 3/20 0.46
GRIN2B Q13224 3/20 0.46
MTNR1B P49286 3/20 0.43
DRD2 P14416 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25163185 1.00 ESR1 (0.52) ESR1ESR2SIGMAR1GRIN1GRIN2B
SCHEMBL28452022 0.92 ESR1 (0.45) ESR1ESR2SIGMAR1GRIN1GRIN2B
SCHEMBL28451201 0.91 GRIN2B (0.50) ESR1ESR2SIGMAR1GRIN1GRIN2B
SCHEMBL28454061 0.90 ESR1 (0.44) ESR1ESR2SIGMAR1GRIN1GRIN2B
SCHEMBL28451558 0.90 SLC6A4 (0.47) ESR1ESR2SIGMAR1GRIN1GRIN2B
SCHEMBL28451705 0.90 OPRM1 (0.46) ESR1ESR2SIGMAR1GRIN1GRIN2B
SCHEMBL28451702 0.90 ESR1 (0.47) ESR1ESR2SIGMAR1GRIN1GRIN2B
SCHEMBL28457249 0.87 ESR1 (0.47) ESR1ESR2SIGMAR1GRIN1GRIN2B
SCHEMBL28451897 0.87 SMPD1 (0.48) SIGMAR1MTNR1BDRD2HTR2A
SCHEMBL28452101 0.87 MTNR1B (0.48) ESR1ESR2SIGMAR1GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122940-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS Versitech Limited (CN) 2023-01-25 EP disclosed
CN-115636840-A Binuclear gold (I) compounds for photocatalytic applications 港大科桥有限公司 2023-01-24 CN disclosed
CN-111592563-A Compound containing carbon-silicon bond and application thereof 中国科学院上海有机化学研究所 2020-08-28 CN disclosed