Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | BCL2 | P10415 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20082221 | 0.89 | PTGS2 (0.40) | PTGS1PTGS2BCL2L1HRH3BCL2 | |
| SCHEMBL19867722 | 0.83 | PTGS1 (0.34) | PTGS1PTGS2BCL2L1BCL2LMNA | |
| SCHEMBL22560741 | 0.82 | PTGS2 (0.45) | PTGS1PTGS2BCL2L1BCL2LMNA | |
| SCHEMBL19183275 | 0.80 | PTGS2 (0.44) | PTGS1PTGS2BCL2L1BCL2 | |
| SCHEMBL19203931 | 0.80 | PTGS2 (0.44) | PTGS1PTGS2BCL2L1BCL2 | |
| SCHEMBL1959392 | 0.79 | PTGS2 (0.45) | PTGS1PTGS2BCL2L1BCL2 | |
| SCHEMBL19145307 | 0.78 | BCL2L1 (0.46) | PTGS1PTGS2BCL2L1HRH3BCL2 | |
| SCHEMBL21851539 | 0.77 | PTGS2 (0.44) | PTGS1PTGS2BCL2L1BCL2 | |
| SCHEMBL23298661 | 0.77 | PTGS2 (0.44) | PTGS1PTGS2BCL2L1BCL2MAPT | |
| SCHEMBL523660 | 0.77 | PTGS2 (0.44) | PTGS1PTGS2BCL2L1BCL2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119560-A1 | APOPTOSIS-INDUCING AGENTS | Shanghai Fochon Pharmaceutical Co., Ltd. (CN) | 2023-01-18 | — | — | EP | disclosed |