SCHEMBL2491769

SCHEMBL2491769

Cc1c(C=O)[nH]c(C=O)c1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
GRIA1 P42261 1/20 0.30
GRIA2 P42262 1/20 0.30
GRIA3 P42263 1/20 0.30
GRIA4 P48058 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18190428 0.81 ALDH1A1 (0.32) ALDH1A1POLBKMT2A
SCHEMBL9738010 0.79 ALDH1A1 (0.31) ALDH1A1POLBKMT2A
SCHEMBL2490933 0.75 KMT2A (0.33) ALDH1A1POLBKMT2A
SCHEMBL11761527 0.75 SMN1; SMN2 (0.38) ALDH1A1POLBKMT2A
SCHEMBL11763540 0.75 ALDH1A1 (0.32) ALDH1A1POLBKMT2A
SCHEMBL7239817 0.73 TYMP (0.48) ALDH1A1POLBKMT2AGRIA1GRIA2
SCHEMBL2543556 0.73 KDR (0.41) ALDH1A1POLBKMT2A
SCHEMBL13488605 0.72 TYMP (0.31) ALDH1A1POLBKMT2A
SCHEMBL18190423 0.71 SMN1; SMN2 (0.50) ALDH1A1POLB
SCHEMBL6400960 0.70 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10570241-B2 Polymers, substrates, methods for making such, and devices comprising the same AVERTICA INC. (US) 2020-02-25 US claimed
CN-105339403-B Polymer, substrate for preparing same, method and device comprising same 艾芙迪卡公司 2018-05-04 CN claimed
EP-2953987-B1 POLYMERS, SUBSTRATES, METHODS FOR MAKING SUCH, AND DEVICES COMPRISING THE SAME AVERTICA INC (US) 2018-04-11 EP claimed
US-20170275410-A1 POLYMERS, SUBSTRATES, METHODS FOR MAKING SUCH, AND DEVICES COMPRISING THE SAME Avertica, Inc. 2017-09-28 US claimed
US-20170044295-A1 POLYMERS, SUBSTRATES, METHODS FOR MAKING SUCH, AND DEVICES COMPRISING THE SAME AVERTICA INC (US) 2017-02-16 US claimed
CN-105339403-A Polymer, substrate for preparing same, method and device comprising same AVERTICA INC 2016-02-17 CN claimed
WO-2016019128-A1 POLYMERS, SUBSTRATES, METHODS FOR MAKING SUCH, AND DEVICES COMPRISING THE SAME AVERTICA INC. (US) 2016-02-04 WO claimed
EP-2953987-A1 POLYMERS, SUBSTRATES, METHODS FOR MAKING SUCH, AND DEVICES COMPRISING THE SAME Avertica Inc. (US) 2015-12-16 EP claimed
WO-2014124122-A1 POLYMERS, SUBSTRATES, METHODS FOR MAKING SUCH, AND DEVICES COMPRISING THE SAME Avertica, Inc. (US) 2014-08-14 WO claimed
US-20140220457-A1 POLYMERS, SUBSTRATES, METHODS FOR MAKING SUCH, AND DEVICES COMPRISING THE SAME Avertica, Inc. (US) 2014-08-07 US claimed
US-20040154109-A1 Composition for dyeing keratin fibers, comprising at least one dialdehyde heterocyclic compound and at least one nitrogen compound L'OREAL S.A. (FR) 2004-08-12 US claimed
EP-1428504-A1 Composition for dyeing keratinous fibres comprising at least a heterocyclic compound and at least a nitrogenous compound L'OREAL (FR) 2004-06-16 EP claimed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-10570241-B2 Polymers, substrates, methods for making such, and devices comprising the same AVERTICA INC. (US) 2020-02-25 US disclosed
EP-2953987-B1 POLYMERS, SUBSTRATES, METHODS FOR MAKING SUCH, AND DEVICES COMPRISING THE SAME AVERTICA INC (US) 2018-04-11 EP disclosed
US-20170275410-A1 POLYMERS, SUBSTRATES, METHODS FOR MAKING SUCH, AND DEVICES COMPRISING THE SAME Avertica, Inc. 2017-09-28 US disclosed
US-7351508-B2 Organophotoreceptors with a charge transport material having multiple vinyl-containing hydrazone groups SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-04-01 US disclosed
US-20060078351-A1 Organophotoreceptors with a charge transport material having multiple vinyl-containing hydrazone groups S-PRINTING SOLUTION CO., LTD. (KR) 2006-04-13 US disclosed
US-20040154109-A1 Composition for dyeing keratin fibers, comprising at least one dialdehyde heterocyclic compound and at least one nitrogen compound L'OREAL S.A. (FR) 2004-08-12 US disclosed
EP-1428504-A1 Composition for dyeing keratinous fibres comprising at least a heterocyclic compound and at least a nitrogenous compound L'OREAL (FR) 2004-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040154109-A1 Composition for dyeing keratin fibers, comprising at least one dialdehyde heterocyclic compound and at least one nitrogen compound KRT18, KRTCAP2, KLK5 ALDH1A1 50/4885POLB 2825/4885KMT2A 861/4885
US-20060078351-A1 Organophotoreceptors with a charge transport material having multiple vinyl-containing hydrazone groups SLC16A7, SLC16A1, SLC16A3 ALDH1A1 695/4885POLB 4183/4885KMT2A 2663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.