Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491769 | 0.70 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL11763540 | 0.70 | ALDH1A1 (0.32) | ALDH1A1RAB9A | |
| SCHEMBL11761527 | 0.70 | SMN1; SMN2 (0.38) | ALDH1A1RAB9A | |
| SCHEMBL2543556 | 0.68 | KDR (0.41) | ALDH1A1RAB9A | |
| SCHEMBL15331397 | 0.65 | ALDH1A1 (0.58) | ALDH1A1RAB9A | |
| SCHEMBL394139 | 0.65 | ALDH1A1 (0.46) | ALDH1A1RAB9A | |
| SCHEMBL11307800 | 0.65 | CYP1A2 (0.57) | ALDH1A1RAB9A | |
| SCHEMBL5358334 | 0.65 | ALDH1A1 (0.39) | ALDH1A1RAB9A | |
| SCHEMBL6088532 | 0.64 | CHEK1 (0.34) | ALDH1A1 | |
| SCHEMBL13303521 | 0.64 | ALDH1A1 (0.39) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861418-B2 | 4-aryl substituted indolinones | SUGEN, INC. (US) | 2005-03-01 | — | — | US | disclosed |