SCHEMBL2491930

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2489505	0.92	HTR7 (0.38)	ALDH1A1HTR7APPHPGDIDO1
	SCHEMBL16268547	0.88	APP (0.46)	ALDH1A1HTR7APPIDO1KDM4E
	SCHEMBL2495623	0.87	TAAR1 (0.46)	ALDH1A1HTR7CD274APPIDO1
	SCHEMBL2491622	0.83	TAAR1 (0.43)	ALDH1A1HTR7CD274APPIDO1
	SCHEMBL694510	0.81	IDO1 (0.56)	ALDH1A1HPGDIDO1MAPT
	SCHEMBL2491945	0.79	FFAR1 (0.36)	ALDH1A1HTR7CD274KDM4E
	SCHEMBL2493864	0.78	ALDH1A1 (0.36)	ALDH1A1CD274HPGDIDO1HSD17B10
	SCHEMBL2491941	0.77	CHRM3 (0.35)	ALDH1A1CD274IDO1L3MBTL1RAB9A
	SCHEMBL2488729	0.76	KDM4E (0.55)	ALDH1A1CD274KDM4EL3MBTL1TSHR
	SCHEMBL2790921	0.74	IDO1 (0.50)	ALDH1A1HTR7APPIDO1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.