SCHEMBL2495623

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2491622	0.93	TAAR1 (0.43)	TAAR1IDO1HTR7APPCD274
	SCHEMBL16268547	0.89	APP (0.46)	TAAR1IDO1HTR7APPALDH1A1
	SCHEMBL2491930	0.87	ALDH1A1 (0.44)	IDO1HTR7APPCD274ALDH1A1
	SCHEMBL2489505	0.85	HTR7 (0.38)	IDO1HTR7APPALDH1A1KDM4E
	SCHEMBL2495001	0.81	TAAR1 (0.40)	TAAR1HTR7CD274MAPTMAPK1
	SCHEMBL2494538	0.79	IDO1 (0.40)	TAAR1IDO1HTR7CD274ALDH1A1
	SCHEMBL22425880	0.78	TAAR1 (0.47)	TAAR1IDO1CD274ALDH1A1MAPT
	SCHEMBL2790921	0.76	IDO1 (0.50)	TAAR1IDO1HTR7APPALDH1A1
	SCHEMBL30317639	0.74	HTR7 (0.64)	TAAR1HTR7APPALDH1A1KDM4E
	SCHEMBL2490820	0.73	TAAR1 (0.39)	TAAR1IDO1CD274MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.