SCHEMBL2491939

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2493494	0.91	ADORA1 (0.40)	CRHR1ADORA1
	SCHEMBL2488675	0.84	KDM4E (0.38)	ARHPGDGCGRMEN1KMT2A
	SCHEMBL2489246	0.76	MAPT (0.39)	MEN1KMT2AMAPTTDP1KDM4E
	SCHEMBL2492131	0.74	GCGR (0.45)	GCGRDHFRPSMB5
	SCHEMBL2491466	0.72	LTA4H (0.40)	DHFRMAPK1KDM4E
	SCHEMBL16559087	0.71	KDM4E (0.41)	ARHPGDMEN1KMT2AATM
	SCHEMBL2492803	0.71	TLR8 (0.41)	HPGDMEN1KMT2AATMMAPT
	SCHEMBL2492230	0.70	GCGR (0.38)	GAAHPGDGCGRDHFRADORA1
	SCHEMBL12983559	0.69	CRHR1 (0.46)	CRHR1GAAHPGDMEN1KMT2A
	SCHEMBL2491463	0.69	GCGR (0.44)	GCGRMAPTDHFRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.