SCHEMBL2491971

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2494412	0.91	MEN1 (0.35)	MEN1KMT2APABPC1USP2ALDH1A1
	SCHEMBL16701641	0.80	TAAR1 (0.41)	MEN1KMT2APABPC1USP2ALDH1A1
	SCHEMBL2490780	0.80	MEN1 (0.46)	MEN1KMT2APABPC1USP2ALDH1A1
	SCHEMBL2488726	0.77	HTR7 (0.50)	MEN1KMT2APABPC1USP2ALDH1A1
	SCHEMBL15859646	0.74	MEN1 (0.64)	MEN1KMT2APABPC1USP2ALDH1A1
	SCHEMBL15859643	0.74	MEN1 (0.72)	MEN1KMT2APABPC1USP2ALDH1A1
	SCHEMBL7063623	0.73	MEN1 (0.62)	MEN1KMT2APABPC1USP2ALDH1A1
	SCHEMBL2491885	0.72	MEN1 (0.39)	MEN1KMT2APABPC1USP2ALDH1A1
	SCHEMBL2492754	0.69	HTR7 (0.48)	MEN1KMT2AUSP2ALDH1A1HSD17B10
	SCHEMBL30231841	0.68	ALDH1A1 (0.54)	MEN1KMT2APABPC1USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.