Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069467 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL24919880 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL24920104 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL9629581 | 0.71 | ALOX5 (0.68) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL24920099 | 0.71 | KDM4E (0.43) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL14632255 | 0.69 | MAOB (0.53) | MAPTMEN1KMT2A | |
| SCHEMBL9629237 | 0.67 | ALOX5 (0.62) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL4186122 | 0.67 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL7861018 | 0.66 | CA12 (0.52) | ALDH1A1GAAMAPTMEN1LMNA | |
| SCHEMBL9630614 | 0.65 | KDM4E (0.72) | KDM4EALDH1A1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004138-A1 | AGONISTS OF TYRO3 AS PROTECTION AGAINST PODOCYTE INJURY IN KIDNEY GLOMERULAR DISEASE | DAS BHASKAR (US) | 2023-01-26 | — | — | WO | disclosed |