Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920103 | 0.81 | — | — | |
| SCHEMBL24920098 | 0.75 | IRAK4 (0.33) | KDM4EMEN1ALDH1A1LMNAGAA | |
| SCHEMBL21730332 | 0.72 | TGFBR1 (0.40) | KDM4EGAA | |
| SCHEMBL24316477 | 0.67 | KDM4E (0.41) | KDM4EALDH1A1GAA | |
| SCHEMBL24920077 | 0.66 | KCNH2 (0.30) | — | |
| SCHEMBL21722503 | 0.66 | ENPP2 (0.38) | — | |
| SCHEMBL20600632 | 0.65 | POLB (0.41) | KDM4EMEN1GAAKMT2A | |
| SCHEMBL30926487 | 0.65 | SCN5A (0.35) | — | |
| SCHEMBL2497482 | 0.64 | CDC7 (0.51) | KDM4EMEN1LMNAGAAMAPT | |
| SCHEMBL25205709 | 0.64 | TGFBR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004138-A1 | AGONISTS OF TYRO3 AS PROTECTION AGAINST PODOCYTE INJURY IN KIDNEY GLOMERULAR DISEASE | DAS BHASKAR (US) | 2023-01-26 | — | — | WO | disclosed |