Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920100 | 0.83 | SNCA (0.33) | — | |
| SCHEMBL19243772 | 0.76 | FLT3 (0.40) | IRAK4FFAR1 | |
| SCHEMBL24919875 | 0.75 | SNCA (0.51) | KDM4EMEN1ALDH1A1LMNAGAA | |
| SCHEMBL24920102 | 0.75 | KDM4E (0.35) | KDM4EMEN1ALDH1A1LMNAGAA | |
| SCHEMBL20600818 | 0.74 | LPL (0.39) | IRAK4FFAR1 | |
| SCHEMBL18041611 | 0.71 | LPL (0.44) | IRAK4FFAR1 | |
| SCHEMBL15288409 | 0.70 | MKNK1 (0.46) | — | |
| SCHEMBL24920074 | 0.70 | IDO1 (0.34) | IRAK4MEN1KMT2A | |
| SCHEMBL18041526 | 0.69 | TGFBR1 (0.42) | FFAR1 | |
| SCHEMBL24920081 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004138-A1 | AGONISTS OF TYRO3 AS PROTECTION AGAINST PODOCYTE INJURY IN KIDNEY GLOMERULAR DISEASE | DAS BHASKAR (US) | 2023-01-26 | — | — | WO | disclosed |