Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557709 | 0.78 | ALDH1A1 (0.44) | CTSDMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL741751 | 0.78 | MEN1 (0.58) | CTSDMEN1KMT2ATDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8550499 | 0.76 | MEN1 (0.56) | CTSDMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL2205442 | 0.76 | SLC6A2 (0.54) | CTSDMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29270208 | 0.75 | CTSD (0.43) | CTSDMEN1KMT2ATDP1L3MBTL1 | |
| Acetic Acid SCHEMBL9853044 | 0.72 | MEN1 (0.53) | CTSDMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL3819697 | 0.72 | SMN1; SMN2 (0.50) | MEN1KMT2AL3MBTL1ALDH1A1HTT | |
| SCHEMBL13731148 | 0.72 | CTSD (0.38) | CTSDMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL7759530 | 0.71 | ALDH1A1 (0.64) | CTSDMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL639563 | 0.71 | ALDH1A1 (0.64) | CTSDMEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550257-A1 | PHARMACEUTICALLY ACTIVE DISUBSTITUTED TRIAZINE DERIVATIVES | Lead Discovery Center GmbH (DE) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011116951-A1 | PHARMACEUTICALLY ACTIVE DISUBSTITUTED TRIAZINE DERIVATIVES | LEAD DISCOVERY CENTER GMBH (DE) | 2011-09-29 | — | — | WO | disclosed |