SCHEMBL2586698

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2463861	0.92	PTPN1 (0.41)	FFAR4FFAR1ALDH2MAOAMAOB
	SCHEMBL2588182	0.90	FFAR4 (0.52)	FFAR4FFAR1L3MBTL1METKDR
	SCHEMBL2492033	0.88	MET (0.41)	FFAR4FFAR1MAOAMAOBMAPT
	SCHEMBL1136343	0.86	FFAR4 (0.40)	FFAR4FFAR1MAOAMAOBMAPT
	SCHEMBL2588036	0.85	MET (0.40)	FFAR4FFAR1SMN1; SMN2MAPTL3MBTL1
	SCHEMBL2586505	0.84	FFAR1 (0.41)	FFAR4FFAR1MAPTNPC1RAB9A
	SCHEMBL1136119	0.82	MAOB (0.40)	MAOAMAOBMETKDRNPC1
	SCHEMBL2588042	0.81	TSHR (0.39)	FFAR4FFAR1MAOBSMN1; SMN2MET
	SCHEMBL1136230	0.81	MGAM (0.40)	ALDH2MAOAMAOBFAAHMET
	SCHEMBL1136154	0.81	PTPN11 (0.40)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.