Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13572986 | 0.81 | LMNA (0.45) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL12142330 | 0.81 | LMNA (0.45) | LMNAPOLBMAPTTP53HSP90AB1 | |
| Hydrochloric Acid SCHEMBL1367050 | 0.80 | LMNA (0.44) | LMNAPOLBMAPTTP53HSP90AB1 | |
| Hydrochloric Acid SCHEMBL1543006 | 0.80 | LMNA (0.44) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL24920575 | 0.80 | LMNA (0.39) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL24921798 | 0.79 | HSP90AB1 (0.47) | LMNAPOLBMAPTHSP90AB1ALDH1A1 | |
| SCHEMBL24920545 | 0.79 | POLB (0.46) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL24920540 | 0.76 | LMNA (0.47) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL26626951 | 0.74 | CYP2C19 (0.47) | POLBHSP90AB1ALDH1A1CYP2C19KDM4E | |
| SCHEMBL17624380 | 0.74 | LMNA (0.39) | LMNAPOLBMAPTTP53HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |