Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | CASP7 | P55210 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920554 | 0.89 | LMNA (0.50) | POLBSMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL24921798 | 0.83 | HSP90AB1 (0.47) | POLBALDH1A1CYP1A2HSD17B10TSHR | |
| SCHEMBL8808226 | 0.79 | ALDH1A1 (0.45) | POLBSMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL25677916 | 0.79 | HTR2C (0.56) | POLBSMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL8898686 | 0.79 | SMN1; SMN2 (0.54) | POLBSMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL24920524 | 0.79 | LMNA (0.39) | POLBSMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL24921047 | 0.78 | ALDH1A1 (0.44) | POLBSMN1; SMN2ALDH1A1CYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL8898072 | 0.78 | SMN1; SMN2 (0.52) | POLBSMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL24920528 | 0.76 | LMNA (0.61) | POLBLMNAMAPTTP53HSP90AB1 | |
| SCHEMBL24920575 | 0.76 | LMNA (0.39) | POLBLMNAMAPTTP53HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |