Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SORD | Q00796 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920524 | 0.80 | LMNA (0.39) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL24921798 | 0.76 | HSP90AB1 (0.47) | LMNAPOLBMAPTHSP90AB1 | |
| SCHEMBL24920545 | 0.76 | POLB (0.46) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL24920540 | 0.73 | LMNA (0.47) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL14094522 | 0.73 | HSP90AB1 (0.49) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL24920528 | 0.72 | LMNA (0.61) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL82292 | 0.71 | ADRA2A (0.41) | — | |
| SCHEMBL13572986 | 0.70 | LMNA (0.45) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL12142330 | 0.70 | LMNA (0.45) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL12969033 | 0.70 | MAOA (0.41) | HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |