Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24922122 | 0.85 | RAB9A (0.40) | RAB9ANPC1ALOX5APARMAPT | |
| SCHEMBL24922191 | 0.85 | RAB9A (0.50) | RAB9ANPC1ALOX5APARMAPT | |
| SCHEMBL24922109 | 0.78 | ACACB (0.37) | ARACACBMAPTTP53HPGD | |
| SCHEMBL24921617 | 0.76 | ACACB (0.36) | ARACACBMAPTTP53HPGD | |
| SCHEMBL24922268 | 0.75 | ACACB (0.44) | RAB9ANPC1ARACACBMAPT | |
| SCHEMBL24921707 | 0.73 | ALDH1A1 (0.48) | RAB9ANPC1ALOX5APMAPTMEN1 | |
| SCHEMBL27234298 | 0.73 | MAPT (0.36) | ALOX5APARMAPTTP53HPGD | |
| SCHEMBL24921980 | 0.73 | MAPT (0.36) | ALOX5APARMAPTTP53HPGD | |
| SCHEMBL24921633 | 0.72 | AR (0.38) | RAB9ANPC1ARMAPTTP53 | |
| SCHEMBL24922739 | 0.72 | RAB9A (0.47) | RAB9ANPC1ALOX5APTP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |