Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24922122 | 0.91 | RAB9A (0.40) | RAB9ANPC1NOTUMSMN1; SMN2HPGD | |
| SCHEMBL24921633 | 0.86 | AR (0.38) | RAB9ANPC1SMN1; SMN2HPGDAR | |
| SCHEMBL24920693 | 0.85 | RAB9A (0.35) | RAB9ANPC1HPGDTLR8AR | |
| SCHEMBL24921652 | 0.83 | TP53 (0.37) | RAB9ANPC1SMN1; SMN2HPGDAR | |
| SCHEMBL24921673 | 0.82 | MAPT (0.43) | RAB9ANPC1SMN1; SMN2HPGDAR | |
| SCHEMBL24921666 | 0.81 | NPC1 (0.36) | RAB9ANPC1SMN1; SMN2HPGDAR | |
| SCHEMBL24922739 | 0.81 | RAB9A (0.47) | RAB9ANPC1NOTUMSMN1; SMN2HPGD | |
| SCHEMBL24920751 | 0.81 | RAB9A (0.47) | RAB9ANPC1NOTUMSMN1; SMN2HPGD | |
| SCHEMBL24921657 | 0.80 | LMNA (0.38) | RAB9ANPC1SMN1; SMN2HPGDAR | |
| SCHEMBL24921672 | 0.80 | NPC1 (0.37) | RAB9ANPC1SMN1; SMN2HPGDAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |