SCHEMBL24920775

SCHEMBL24920775

COc1ncc(C(C)O)nn1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APLNR P35414 2/20 0.35
FTO Q9C0B1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17820131 0.72 FTO (0.37) APLNRFTO
SCHEMBL5842338 0.70 APLNR (0.37) APLNR
SCHEMBL24920783 0.69 APLNR (0.58) APLNR
SCHEMBL24215353 0.68 APLNR (0.35) APLNR
SCHEMBL19673045 0.67
SCHEMBL24384648 0.67 NNMT (0.42) APLNR
SCHEMBL24920773 0.67 NNMT (0.42) APLNR
SCHEMBL24922478 0.67 MAPK9 (0.42)
SCHEMBL4278538 0.65 OGA (0.36)
SCHEMBL24193107 0.64 PDCD1 (0.33) APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023006097-A1 BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER 海创药业股份有限公司 2023-02-02 WO disclosed