Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 11/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920384 | 0.81 | HCRTR1 (0.47) | HCRTR1HCRTR2MAT2AOGA | |
| SCHEMBL24921179 | 0.75 | LOX (0.39) | MAT2ADYRK1AACVR2ATGFBR2 | |
| SCHEMBL24922002 | 0.74 | MEN1 (0.30) | MEN1CYP1A2KMT2A | |
| SCHEMBL24921165 | 0.73 | ALOX5 (0.40) | CYP1A2KMT2AOGA | |
| SCHEMBL16547539 | 0.72 | NPSR1 (0.43) | HCRTR1HCRTR2MAT2AOGAACVR2A | |
| SCHEMBL24920770 | 0.72 | PDE10A (0.42) | CYP1A2DYRK1A | |
| SCHEMBL24921999 | 0.71 | OGA (0.33) | HCRTR1HCRTR2OGAACVR2ATGFBR2 | |
| SCHEMBL24921589 | 0.71 | MEN1 (0.44) | MEN1KMT2AOGA | |
| SCHEMBL24920876 | 0.71 | HCRTR1 (0.30) | HCRTR1HCRTR2 | |
| SCHEMBL24921166 | 0.70 | CCR1 (0.46) | CYP1A2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |