Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921499 | 0.80 | KDM4E (0.32) | — | |
| SCHEMBL24921999 | 0.77 | OGA (0.33) | — | |
| SCHEMBL24921989 | 0.75 | KDM4E (0.37) | CYP1A2KMT2A | |
| SCHEMBL24921997 | 0.75 | SIRT6 (0.35) | — | |
| SCHEMBL24920786 | 0.74 | HCRTR1 (0.37) | MEN1CYP1A2KMT2A | |
| SCHEMBL24921589 | 0.73 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL24921177 | 0.71 | GABRG2 (0.34) | MEN1CYP1A2KMT2A | |
| SCHEMBL24920876 | 0.70 | HCRTR1 (0.30) | — | |
| SCHEMBL24920819 | 0.69 | CYP2C19 (0.45) | — | |
| SCHEMBL24922528 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |