Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.30 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.30 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.30 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920789 | 0.82 | HCRTR2 (0.37) | HCRTR1HCRTR2GUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL24921999 | 0.74 | OGA (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL24922544 | 0.73 | PIK3CA (0.36) | — | |
| SCHEMBL24920813 | 0.73 | PDK2 (0.37) | — | |
| SCHEMBL24921149 | 0.71 | ATM (0.36) | — | |
| SCHEMBL24920786 | 0.71 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL24920837 | 0.71 | ALKBH1 (0.34) | — | |
| SCHEMBL24922002 | 0.70 | MEN1 (0.30) | — | |
| SCHEMBL24920767 | 0.70 | ADORA2A (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL9977648 | 0.69 | LMNA (0.36) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |