Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 5/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096815 | 0.80 | NPC1 (0.56) | NPC1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8363953 | 0.77 | ADORA2A (0.44) | HCRTR1HCRTR2NPC1MAPTKDM4E | |
| SCHEMBL24920384 | 0.77 | HCRTR1 (0.47) | HCRTR1HCRTR2OGA | |
| SCHEMBL28020279 | 0.77 | NOTUM (0.44) | HCRTR1HCRTR2OGANOTUM | |
| SCHEMBL16815696 | 0.76 | L3MBTL1 (0.39) | NPC1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24921068 | 0.76 | RXRA (0.39) | NPC1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9522293 | 0.75 | MEN1 (0.49) | HCRTR1HCRTR2NPC1MAPTKDM4E | |
| SCHEMBL3404328 | 0.75 | ALDH1A1 (0.46) | NPC1MAPTKDM4EALDH1A1ADORA2A | |
| SCHEMBL9520789 | 0.75 | KDM4E (0.50) | NPC1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10575533 | 0.75 | HCRTR1 (0.42) | HCRTR1HCRTR2NPC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |
| CN-104725397-A | Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-06-24 | — | — | CN | disclosed |