Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920403 | 0.81 | HCRTR1 (0.32) | — | |
| SCHEMBL24921166 | 0.75 | CCR1 (0.46) | PDE10ALMNA | |
| SCHEMBL24921177 | 0.75 | GABRG2 (0.34) | PDE10A | |
| SCHEMBL24921264 | 0.73 | CHRNB2 (0.44) | LMNA | |
| SCHEMBL2614481 | 0.72 | — | — | |
| SCHEMBL24921989 | 0.71 | KDM4E (0.37) | PDE10A | |
| SCHEMBL24921560 | 0.71 | EGLN1 (0.37) | PDE10AGRM5LMNA | |
| SCHEMBL24921553 | 0.70 | HTT (0.53) | LMNA | |
| SCHEMBL24921999 | 0.70 | OGA (0.33) | PDE10ALMNA | |
| SCHEMBL24921968 | 0.70 | PDE10A (0.37) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |