Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.32 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920804 | 0.81 | PDK2 (0.37) | PDK2CYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL24921540 | 0.74 | PDE10A (0.36) | PDE10ACYP1A2CYP3A4USP2CYP2C19 | |
| SCHEMBL24921593 | 0.73 | HCRTR1 (0.33) | PDE10ACYP1A2 | |
| SCHEMBL24920876 | 0.73 | HCRTR1 (0.30) | — | |
| SCHEMBL24920900 | 0.71 | PDK2 (0.35) | PDK2CYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL24921149 | 0.71 | ATM (0.36) | CYP3A4CYP2C9CYP2D6NR1H2NR1H3 | |
| SCHEMBL24920770 | 0.71 | PDE10A (0.42) | PDE10ACYP1A2CYP3A4CYP2D6USP2 | |
| SCHEMBL24921968 | 0.70 | PDE10A (0.37) | PDE10A | |
| SCHEMBL24920808 | 0.70 | ALDH1A1 (0.38) | PDK2CYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL14972263 | 0.69 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C9USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |