Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921172 | 0.75 | CCR1 (0.59) | PTGDRNPC1RAB9AKMT2AMAPK14 | |
| SCHEMBL24920835 | 0.75 | NOTUM (0.51) | KMT2ATLR8ALDH1A1MAPTHPGD | |
| SCHEMBL24920867 | 0.74 | CNR2 (0.37) | PTGDRNPC1RAB9AKMT2AMAPT | |
| SCHEMBL12923721 | 0.73 | NPC1 (0.44) | PTGDRNPC1RAB9AKMT2AMAPK14 | |
| SCHEMBL12923984 | 0.73 | CHRNB2 (0.46) | NPC1RAB9AKMT2AMAPK14ALDH1A1 | |
| SCHEMBL24920815 | 0.72 | CCR1 (0.34) | — | |
| SCHEMBL24921142 | 0.71 | GABRG2 (0.44) | NPC1RAB9AKMT2AMAPK14TLR8 | |
| SCHEMBL24921547 | 0.71 | NPC1 (0.37) | PTGDRNPC1RAB9AKMT2AMAPK14 | |
| SCHEMBL24920812 | 0.71 | MAPT (0.44) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL24921502 | 0.70 | NPC1 (0.40) | PTGDRNPC1RAB9AKMT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |