Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23710146 | 0.79 | RPS6KB1 (0.34) | CARM1PRMT6ADH1BADH1CADH1A | |
| SCHEMBL24920853 | 0.78 | — | — | |
| SCHEMBL30832040 | 0.78 | L3MBTL1 (0.44) | L3MBTL1CARM1PRMT6CXCR4ADH1B | |
| SCHEMBL23710148 | 0.77 | SIGMAR1 (0.46) | CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL30832002 | 0.76 | L3MBTL1 (0.43) | L3MBTL1CARM1PRMT6CXCR4ADH1B | |
| SCHEMBL23516990 | 0.76 | CNR2 (0.35) | — | |
| SCHEMBL23573235 | 0.75 | CYP2D6 (0.47) | L3MBTL1CXCR4 | |
| SCHEMBL1488427 | 0.73 | NCF1 (0.52) | L3MBTL1CARM1PRMT6ROCK2ROCK1 | |
| Formic Acid SCHEMBL28967734 | 0.73 | — | — | |
| SCHEMBL28206026 | 0.73 | HSD17B10 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |