SCHEMBL24922425

SCHEMBL24922425

C/N=C\c1ccc(C=N)s1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.40
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CASP1 P29466 1/20 0.32
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23608992 0.74
SCHEMBL3158483 0.73
SCHEMBL22055516 0.70 MAPK1 (0.49) RAB9AMAPTSMN1; SMN2NPC1CASP3
SCHEMBL14606380 0.69
SCHEMBL20151074 0.64 GAA (0.36) RAB9AMAPTSMN1; SMN2NPC1CASP3
SCHEMBL13514040 0.64
SCHEMBL19300886 0.64 TDP1 (0.33) RAB9AMAPTSMN1; SMN2NPC1LMNA
SCHEMBL18867349 0.63 HPGD (0.54) RAB9AMAPTSMN1; SMN2NPC1LMNA
SCHEMBL8946056 0.60
SCHEMBL15133699 0.60 RAB9A (0.38) RAB9AMAPTSMN1; SMN2NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11569530-B2 Silicon-based energy storage devices with functional thiophene compounds or derivatives of thiophene containing electrolyte additives ENEVATE CORPORATION (US) 2023-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11569530-B2 Silicon-based energy storage devices with functional thiophene compounds or derivatives of thiophene containing electrolyte additives TST, SELENOI, SELE RAB9A 3400/4885MAPT 2243/4885SMN1; SMN2 2053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.