SCHEMBL2492279

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2494574	0.90	LMNA (0.60)	LMNAKMT2AMEN1MAPTNR1I2
	SCHEMBL4362613	0.89	KMT2A (0.50)	LMNAKMT2AMEN1MAPTNR1I2
	SCHEMBL4367374	0.89	KMT2A (0.50)	LMNAKMT2AMEN1MAPTNR1I2
	SCHEMBL2490797	0.83	HCRTR1 (0.59)	LMNAKMT2AMEN1MAPTALDH1A1
	SCHEMBL124950	0.82	ALDH1A1 (0.71)	LMNAKMT2AMEN1MAPTNR1I2
	SCHEMBL3135517	0.82	LMNA (0.74)	LMNAKMT2AMEN1MAPTNR1I2
	SCHEMBL31643582	0.82	ALDH1A1 (0.71)	LMNAKMT2AMEN1MAPTNR1I2
	1,2-Dipropoxybenzene SCHEMBL29428926	0.82	CYP1A2 (0.56)	LMNAKMT2AMEN1MAPTHTR2B
	1,2-Dipropoxybenzene SCHEMBL578657	0.82	CYP1A2 (0.56)	LMNAKMT2AMEN1MAPTHTR2B
	SCHEMBL1985	0.81	LMNA (0.55)	LMNAKMT2AMEN1MAPTNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.