Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4362613 | 0.96 | KMT2A (0.50) | KMT2AMEN1HIF1ALMNAMAPT | |
| SCHEMBL4366626 | 0.91 | LMNA (0.54) | KMT2AMEN1HIF1ALMNAMAPT | |
| SCHEMBL2492279 | 0.89 | LMNA (0.53) | KMT2AMEN1HIF1ALMNAMAPT | |
| SCHEMBL4365539 | 0.88 | LMNA (0.54) | KMT2AMEN1HIF1ALMNAMAPT | |
| SCHEMBL4363572 | 0.85 | MEN1 (0.56) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL8142503 | 0.85 | LMNA (0.63) | KMT2AMEN1LMNAMAPTNR1I2 | |
| SCHEMBL5820347 | 0.85 | LMNA (0.63) | KMT2AMEN1LMNAMAPTNR1I2 | |
| SCHEMBL5820306 | 0.85 | LMNA (0.63) | KMT2AMEN1LMNAMAPTNR1I2 | |
| SCHEMBL30444952 | 0.83 | DRD2 (0.61) | KMT2AMEN1HIF1ALMNAMAPT | |
| SCHEMBL5598745 | 0.83 | DRD2 (0.61) | KMT2AMEN1HIF1ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2749566-B1 | SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE | AIST (JP) | 2018-05-09 | — | — | EP | disclosed |
| US-9428809-B2 | Solid-phase carrier for aminated oligonucleotide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2016-08-30 | — | — | US | disclosed |
| US-20140187724-A1 | SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2014-07-03 | — | — | US | disclosed |
| EP-2749566-A1 | SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE | National Institute of Advanced Industrial Science And Technology (JP) | 2014-07-02 | — | — | EP | disclosed |
| EP-1908829-B1 | OLIGONUCLEOTIDE PROBE | NAT INST OF ADVANCED IND SCIEN (JP) | 2014-01-08 | — | — | EP | disclosed |
| US-7491857-B2 | Oligonucleotide probe | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2009-02-17 | — | — | US | disclosed |
| US-20080227968-A1 | Oligonucleotide Probe | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-18 | — | — | US | disclosed |
| EP-1908829-A1 | OLIGONUCLEOTIDE PROBE | National Institute of Advanced Industrial Science and Technology (JP) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227968-A1 | Oligonucleotide Probe | APEX1, RNGTT, RNASEH1 | KMT2A 3173/4885MEN1 1946/4885HIF1A 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.